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Станислав Валерьевич Пугачев
Евгения Александровна Каменева
Надежда Юрьевна Шалякина
Наталья Александровна Ануфриева
Евгений Валерьевич Григорьев
Вадим Гельевич Мозес

Abstract

Amyotrophic lateral sclerosis (ALS) is rare neurodegenerative disease that needs prolonged respiratory therapy. Ventilator respiratory support is strongly requested for intensive care in different critical illnesses, but it is associated with high risk of specific complications. Latter could rarely be avoided especially in cases of prolong mechanically ventilation that provided in cases of central nervous system injury, major trauma, persisting organ dysfunction etc. Despite the fact of incurable loss of spontaneous breathing in patients with ALS, logistic path of outpatient palliative care provision is absent. Nonetheless outpatient individual intensive care, for respiratory tract particularly, makes possible to avoid serious ventilator-associated adverse events for a long period.

Keywords

amyotrophic lateral sclerosis, outpatient mechanical ventilation, ventilator-associated complication

Author Biographies

Станислав Валерьевич Пугачев,
candidate of medical sciences, doctor anesthesiologist-resuscitator
Евгения Александровна Каменева,
doctor of medical sciences, deputy chief physician for anesthesiology service
Надежда Юрьевна Шалякина,
candidate of medical sciences, head of the department of neurology
Наталья Александровна Ануфриева,
anesthesiologist-resuscitator
Евгений Валерьевич Григорьев,
doctor of medical sciences, professor, deputy chief physician; head of the department of anesthesiology, reanimatology, traumatology and orthopedics
Вадим Гельевич Мозес,
doctor of medical sciences, head of obstetrics and gynecology department N 1

Article Details

Information about financing and conflict of interests

The study had no sponsorship.
The authors declare that they have no apparent or potential conflicts of interest related to the publication of this article.

How to Cite

Пугачев, С. В., Каменева, Е. А., Шалякина, Н. Ю., Ануфриева, Н. А., Григорьев, Е. В., & Мозес, В. Г. (2020). PROLONGED OUTPATIENT MECHANICAL VENTILATION AND INTENSIVE CARE IN PATIENT WITH AMYOTROPHIC LATERAL SCLEROSIS. CASE REPORT. Medicine in Kuzbass, 19(4), 85-89. https://doi.org/10.24411/2687-0053-2020-10044

References

Al-Chalabi A, Hardiman O. The epidemiology of ALS: a conspiracy of genes, environment and time. Nature Reviews Neurology. 2013; 9(11): 617-628

Salameh J, Brown RJr, Berry J. Amyotrophic Lateral Sclerosis: Review. Seminars Neurology. 2015; 35: 469-476

Bensimon G, Lacomblez L, Delumeau J, Bejuit R. A study of riluzole in the treatment of advanced stage or elderly patients with amyotrophic lateral sclerosis. J of Neurol. 2002; 249(5): 609-615. doi: 10.1007/s004150200071

Cappella M, Ciotti C, Cohen-Tannoudji M, Biferi MG. Gene Therapy for ALS – a Perspective. Int J Mol Sci. 2019; 20(18): 4388. https://doi.org/10.3390/ijms20184388

Peña-López Y, Ramirez-Estrada S, Eshwara V, Rello J. Limiting ventilator-associated complications in ICU intubated subjects: strategies to prevent Ventilator-associated events and improve outcomes. Expert Rev Respir Med. 2018; 12(12): 1037-1050. doi: 10.1080/17476348.2018.1549492

Spalding D, Cripps M, Minshall C. Ventilator-Associated Pneumonia: New Definitions. Critical Care Clinics. 2017; 33(2): 277-292. doi: 10.1016/j.ccc.2016.12.009

Van Vught L, Klowenberg P, Spitoni C, Scicluna BP, Wiewel MA, Horn J et al. Incidence, Risk Factors, and Attributable Mortality of Secondary Infections in the Intensive Care Unit After Admission for Sepsis. JAMA. 2016; 315(14): 1469-1479. doi: 10.1001/jama.2016.2691

Klompas M. What is new in the prevention of nosocomial pneumonia in the ICU? Curr Opin Crit Care. 2017; 23(5): 378-384. doi: 10.1097/MCC.0000000000000443

Fasano A, Fini N, Ferraro D, Ferri L, Vinceti M, Mandrioli J. Percutaneous endoscopic gastrostomy, body weight loss and survival in amyotrophic lateral sclerosis: a population-based registry study. Amyotroph Lateral Scler Frontotemporal Degener. 2017; 18(3-4): 233-242. doi: 10.1080/21678421.2016.1270325

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