PRIMARY HYPERALDOSTERONISM: A LONG ROAD TO DIAGNOSTICS AND EFFECTIVE TREATMENT (CLINICAL CASE)

Article Sidebar

HTML (Russian) PDF (Russian)
Issue:
Section:
CASE HISTORY
Published:
2023-08-22
DOI:
https://doi.org/10.24412/2687-0053-2023-3-66-69

Main Article Content

Евгения Петровна Каширина
head of the department of endocrinology
Юлия Борисовна Королёва
Novokuznetsk City Clinical Hospital N 1 named after G.P. Kurbatov
Елена Жоржевна Каширина
Novokuznetsk State Institute for Postgraduate Medical Education
Константин Сергеевич Хохлов
candidate of medical sciences, docent of the department of endocrinology and diabetology

Abstract

Primary hyperaldosteronism (PHA), which was considered a rare disease, according to the results of studies, is the cause of arterial hypertension (AH) in 5-15 % of cases, which puts it in the first place in the structure of secondary hypertension. PHA is a serious disease, since high values of aldosterone, in addition to its indirect effect, have a direct damaging effect on the myocardium, blood vessels, and renal interstitium. Timely diagnosis allows you to either completely cure the patient of hypertension, or use effective therapy. This clinical observation confirms the importance of timely diagnosis, surgical treatment.

Keywords

primary hyperaldesidism, aldosteroma, arterial hypertension, aldosterone, adrenal glands

Author Biographies

Евгения Петровна Каширина,
candidate of medical sciences, docent of the department of endocrinology and diabetology
Юлия Борисовна Королёва,
candidate of medical sciences, head of the surgical department,
Елена Жоржевна Каширина,
candidate of medical sciences, docent of the department of endocrinology and diabetology
Константин Сергеевич Хохлов,
Novokuznetsk City Clinical Hospital N 1 named after G.P. Kurbatov

Article Details

Information about financing and conflict of interests

The study had no sponsorship.
The authors declare that they have no apparent or potential conflicts of interest related to the publication of this article.
© Евгения Петровна Каширина, Юлия Борисовна Королёва, Елена Жоржевна Каширина, Константин Сергеевич Хохлов, 2023


Creative Commons License  This work is licensed under a Creative Commons Attribution 4.0 License.

How to Cite

Каширина, Е. П., Королёва, Ю. Б., Каширина, Е. Ж., & Хохлов, К. С. (2023). PRIMARY HYPERALDOSTERONISM: A LONG ROAD TO DIAGNOSTICS AND EFFECTIVE TREATMENT (CLINICAL CASE). Medicine in Kuzbass, 22(3), 66-69. https://doi.org/10.24412/2687-0053-2023-3-66-69

References

Melnichenko GA, Platonova NM, Beltsevich DG, Yukina MYu, Molashenko NV, Troshina EA. Primary hyperaldosteronism: diagnosis and treatment. A new look at the problem. Based on the materials of the Draft Clinical Guidelines of the Russian Association of Endocrinologists for the Diagnosis and Treatment of Primary Hyperaldosteronism. Consilium Medicum. 2017; 19(4): 75-85. Russian (Мельниченко Г.А., Платонова Н.М., Бельцевич Д.Г., Юкина М.Ю, Молашенко Н.В., Трошина Е.А. Первичный гиперальдостеронизм: диагностика и лечение. Новый взгляд на проблему. По материалам Проекта клинических рекомендаций Российской ассоциации эндокринологов по диагностике и лечению первичного гиперальдостеронизма //Consilium Medicum. 2017. Т. 19. № 4. С. 75-85)

Milliez P, Girerd X, Plouin PF, Blacher J, Safar ME, Mourad J-J. Evidence for an increased rate of cardiovascular events in patients with primary aldosteronism. J Am Coll Cardiol. 2005; 45: 1243-1248. doi: 10.1016/j.jacc.2005.01.015

Rogal EYu, Beltsevich DG, Fadeev VV, Molashenko NV, Melnichenko GA. Diagnosis of primary hyperaldosteronism. Problems of endocrinology. 2010; 56(2): 4752. Russian (Рогаль Е.Ю., Бельцевич Д.Г., Фадеев В.В., Молашенко Н.В., Мельниченко Г.А. Диагностика первичного гиперальдостеронизма //Проблемы эндокринологии. 2010. Т. 56, № 2. С. 4752

Blumenfeld JD, Sealey JE, Schlussel Y, Vaughan ED Jr, Sos TA, Atlas SA, et al. Diagnosis and treatment of primary hyperaldosteronism. Ann Intern Med. 1994; 121: 877-885. doi: 10.7326/0003-4819-121-11-199412010-00010

Harris DA, Au-Yong I, Basnyat PS, Sadler GP, Wheeler MH. Review of surgical management of aldosterone secreting tumours of the adrenal cortex. Eur J Surg Oncol. 2003; 29: 467-474. doi: 10.1016/s0748-7983(03)00051-9

Rossi E, Regolisti G, Negro A, Sani C, Davoli S, Perazzoli F. High prevalence of primary aldosteronism using postcaptopril plasma aldosterone to renin ratio as a screening test among Italian hypertensives. Am J Hypertens. 2002; 15: 896-902. doi: 10.1016/s0895-7061(02)02969-2

Young WF. Jr. Minireview: primary aldosteronism – changing concepts in diagnosis and treatment. Endocrinology. 2003; 144: 2208-2213. doi: 10.1210/en.2003-0279

Downloads

Download data is not yet available.

Most read articles by the same author(s)