Main Article Content

Семен Вадимович Зотов
Полина Юрьевна Мотырева
Виталий Михайлович Кулешов
Борис Исаевич Айзикович
Виктория Васильевна Лихачева
Сергей Николаевич Филимонов

Abstract

The aim of the research: to evaluate the effect of transvaginal punction of the endometrioid cyst on the ovarian reserve of patients with infertility.

Materials and methods: the study analyzed 65 patients who were planning ART programs and underwent unilateral endometriod cyst puncture with a volume of up to 40 mm, and 69 patients who were operated on in the volume of endometrioma capsule exfoliation with a diameter of up to 40 mm. Before and after the interventions, the parameters of the hormones AMH and FSH, the number of antral follicles (NAF), the volume of the ovary, and the level of the cancer marker CA-125 were evaluated.

Results: after the punction, in contrast to the operation, there was no significant decrease in AMH and NAF parameters. The level of FSH also did not change between the punctated patients, while the operated patients showed an increase in FSH from 6.7 ± 0.5 to 9.1 ± 0.4 mME/ml, a decrease in AMH from 2.0 ± 0.3 to 1.1 ± 0.1 ng/ml, and a decrease in NAF from 8.1 ± 0.7 to 4.0 ± 0.8 three months after surgery. The average values of AMH, FSH, and NAF remained unchanged in the group of punctated patients.

Conclusion: it has been shown that cyst punction does not reduce ovarian reserve, in contrast to laparoscopic cystectomy, and can be considered as an alternative approach for women with endometriod cyst planning ART. Puncture and aspiration of the contents of the endometriod cyst can serve as a factor in the rapid onset of pregnancy, which in itself is an alternative to hormonal treatment of endometriosis.

Keywords

endometriosis, endometrioma, endometriod cyst, puncture, ovarian reserve, infertility, assisted reproductive technologies

Author Biographies

Семен Вадимович Зотов,
obstetrician-gynecologist, head of the ART department
Полина Юрьевна Мотырева,
biologist, laboratory of medical genetics
Виталий Михайлович Кулешов,
doctor of medical sciences, professor, department of obstetrics and gynecology
Борис Исаевич Айзикович,
doctor of medical sciences, professor
Виктория Васильевна Лихачева,
doctor of medical sciences, docent, department of obstetrics and gynecology
Сергей Николаевич Филимонов,

Filimonov Sergey Nikolaevich

M.D., Ph.D., Professor. Chief.

Article Details

Information about financing and conflict of interests

The study had no sponsorship.
The authors declare that they have no apparent or potential conflicts of interest related to the publication of this article.

How to Cite

Зотов, С. В., Мотырева, П. Ю., Кулешов, В. М., Айзикович, Б. И., Лихачева, В. В., & Филимонов, С. Н. (2021). ADVANTAGES OF REDUCING THERAPY OF ENDOMETRIOD CYSTS BY COMPARISON WITH LAPAROSCOPIC EXCISION BEFORE IVF PROGRAMS. Medicine in Kuzbass, 20(1), 26-31. https://doi.org/10.24411/2687-0053-2021-10005

References

Vasilyeva AA. Management of patients with ovarian endometriosis (retrospective analysis and literature review). J Obstet and Women's Dis. 2017; 66: 103-104. Russian (Васильева А.А. Ведение пациенток с эндометриозом яичников (ретроспективный анализ и обзор литературы) //Журнал акушерства и женских болезней. 2017. Т. 66. С. 103-104)

Zulumyan TN. Endometrioid ovarian cysts and infertility: ways to overcome them. Obstetrics and gynecology: News. Opinions. Education. 2017; 17(3): 92-97. Russian (Зулумян Т.Н. Эндометриоидные кисты яичников и бесплодие: пути преодоления //Акушерство и гинекология: Новости. Мнения. Обучения. 2017. T. 17, № 3. С. 92-97)

Goodman LR, Goldberg JM, Flyckt RL, Gupta M, Harwalker J, Falcone T. Effect of surgery on ovarian reserve in women with endometriomas, endometriosis and controls. Am J Obstet Gynecol. 2016; 215(5): 589

Wang Y, Ruan X, Lu D, Sheng J, Mueck AO. Effect of laparoscopic endometrioma cystectomy on anti-Müllerian hormone (AMH) levels. Gynecol Endocrinol. 2019: 35(6): 494-497

Muzii L, Di Tucci C, Di Feliciantonio M, Galati G, Verrelli L, Donato VD, et al. Management of Endometriomas. Semin Reprod Med. 2017; 35(1): 25-30

Jiang D, Nie X. Effect of endometrioma and its surgical excision on fertility (Review). Exp Ther Med. 2020; 20(5): 114

Kuzmina NS, Bezhenar VF, Kalugina AS. Endometriosis and infertility. Surgery or assisted reproductive technologies? Archive of Obstetrics and Gynecology named after V. F. Snegirev. 2018; 5(1): 31-36. Russian (Кузьмина Н.С., Беженарь В.Ф., Калугина А.С. Эндометриоз и бесплодие. Операция или вспомогательные репродуктивные технологии? //Архив акушерства и гинекологии им. В.Ф. Снегирева. 2018. T. 5, № 1. C. 31-36)

Khamzin IZ, Shuiskaya DA, Mesropyan ED, Stepanyan ES. Influence of bipolar coagulation (BOD) on ovarian reserve (OR) during enucleation of endometrioid cysts. Journal of Obstetrics and Women's Diseases. 2016; 65(5): 64-65. Russian (Хамзин И.З., Шуйская Д.А., Месропян Э.Д., Степанян Э.С. Влияние биполярной коагуляции (БПК) на овариальный резерв (ОP) при энуклеации эндометриоидных кист //Журнал акушерства и женских болезней, 2016. T. 65, № 5. C. 64-65)

Popov EN, Rusina EI, Sudakov DS, Dymarskaya YuR, Koleboshina MA. Alternative method of surgical treatment of endometrioid ovarian tumors from the standpoint of ovarian reserve preservation. Journal of Obstetrics and Women's Diseases. 2019; 68(5): 55-62. Russian (Попов Э.Н., Русина Е.И., Судаков Д.С., Дымарская Ю.Р., Колебошина М.А. Альтернативный метод хирургического лечения эндометриоидных опухолей яичников с позиций сохранения овариального резерва //Журнал акушерства и женских болезней. 2019. T. 68, № 5. C. 55-62)

Shaltout MF, Elsheikhah A, Maged AM, Elsherbini MM, Zaki SS, Dahab S, Elkomy RO. A randomized controlled trial of a new technique for laparoscopic management of ovarian endometriosis preventing recurrence and keeping ovarian reserve. J Ovarian Res. 2019; 12(1): 66

Annenkova EI. Versions and contraversions of treatment of patients with endometrioid ovarian cysts and infertility. Obstetrics and gynecology: News. Opinions. Education. 2018; 21(3): 97-104. Russian (Анненкова Е.И. Версии и контраверсии лечения пациенток с эндометриоидными кистами яичников и бесплодием //Акушерство и гинекология: Новости. Мнения. Обучения. 2018. T. 21, № 3. C. 97-104)

Rudakova EB, Strizhova TV, Fedorova EA, Zamakhovskaya LYu. Opportunities for improving the effectiveness of in vitro fertilization programs in «difficult» patients. Lechashchiy vrach. 2019; 12: 14-19. Russian (Рудакова Е.Б., Стрижова Т.В., Федорова Е.А., Замаховская Л.Ю. Возможности улучшения результативности программ экстракорпорального оплодотворения у «трудных» пациенток //Лечащий врач. 2019. № 12. C. 14-19)

Kim JJ, Kurita T, Bulun SE. Progesterone action in endometrial cancer, endometriosis, uterine fibroids, and breast cancer. Endocr Rev. 2013; 34(1): 130-162

Krasnopolskaya KV. Treatment of infertility in endometriosis: the view of a reproductologist. M.: «MEDpress-inform», 2019. Russian (Краснопольская К.В. Лечение бесплодия при эндометриозе: взгляд репродуктолога. М.: «МЕДпресс-информ», 2019)

Downloads

Download data is not yet available.

Most read articles by the same author(s)

<< < 2 3 4 5 6 7 8 9 10 11 > >>