GRAVIDARY HOMEOSTASIS IN PREGNANT WOMEN WITH UNDERWEIGHT
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Abstract
In recent years considerable success has been achieved in reducing obstetric and perinatal complications in various pathological conditions during pregnancy and childbirth. However, many aspects of obstetrics, theoretical and practical, remain unresolved. A promising direction are the new methodological approaches to clinical research methods of physiological and complicated pregnancy. One of such directions is the study of the gravidary homeostasis. The study of the gravidary homeostasis in pregnant women with underweight opens up fundamentally new ways to reduce the obstetric and perinatal complications.
The aim – was to study the gravidar homeostasis in pregnant women with a body weight deficit.
Materials and methods. A survey of 50 pregnant women with a deficit of body weight and their fetuses (the main group). The comparison group consisted of 50 pregnant women with normal body weight and their fruits. Neurovegetative regulation of the heart rhythm of the mother and fetus was studied by the method of spectral and mathematical analysis of the variability of the heart rhythm.
Results. When registering the initial profile of the heart rhythm, only 16 % of women with body weight deficit of the cardiothoracic wave SPM were within the conditional norm (92 %; p < 0,001). An increase in the SPM waves of cardiac rhythm (hyperadaptive state) due to VLF and LF-components of the spectrum was recorded in 48 % of women (6 %; p < 0,001). In 36 % of pregnant SPM waves, cardiac rhythm was characterized by a general depression of the spectrum (2 %; p < 0,001). In carrying out the functional loading test (hyperventilation), hyperadaptive stress responses (10 %; p < 0,001) prevailed in 50 % of cases. During the recovery period, 60 % of pregnant women showed a decrease in the adaptive mechanisms of the mother's body (12 %; p < 0,001). The indices of the cardiac rhythm wave fetal wave in a mother with a body weight deficit in 60 % were characterized as a hyperadaptive state (8 %; p < 0,001).
Conclusion. Investigation of the gravidar homeostasis in pregnant women with a deficiency of body weight opens new possibilities for reducing obstetric and perinatal complications. The mother's homeostasis with a deficiency in body weight was characterized by a pronounced activation of the sympathoadrenal system, the voltage of the compensatory mechanisms. The fetus experienced a gradual decrease in the effectiveness of its own regulatory influences on the part of the neurovegetative system on the heart rhythm.
Keywords
Author Biographies
Елена Владимировна Рудаева,
candidate of medical sciences, docent, chair of obstetrics and gynecology N 1Галина Александровна Ушакова,
Ushakova Galina Aleksandrovna
MD, PhD, professor
She is the Honoured Doctor of the Russian Federation, the Head of the Department of Obstetrics and Gynaecology, an academician of the Russian Academy of Natural Sciences, the founder of the Scientific School of the Preservation of Medical and Biological Reserves of Fertility.
After graduating from high school she entered Tomsk State Medical Institute and graduated in 1960. She had been working as an obstetrics and gynecology doctor in maternity hospitals of Kemerovo and Novosibirsk region for 3 years. From 1963 to 1966 she studied at post-graduate school at the Department of Obstetrics and Gynaecology of Kemerovo Medical Institute. After her post-graduate studies and the defense of candidate thesis about “Metrohemostat in the prevention and treatment of early postpartum haemorrhage”, she started to work as an assistant at the Department. In 1985 she defended her doctoral thesis “The establishment of the reproductive function of females and the basis for the primary prevention of its abnormalities”, took a degree of a Professor and became the Head of the Department of Obstetrics and Gynaecology of Kemerovo Medical Institute.
The priorities for her and her co-workers were the social and demographic problems in the region, so their work was aimed at preservation of medical and biological reserves of fertility.
She developed the scientific basis and organizational forms of reproductive health care of females on the stages of childhood, puberty, fertile period.
Another one priority is the study of the regulatory, energetic and metabolic processes in the mother-placenta-fetus system, in the case of physiological and complicated pregnancy.
Under her supervision 24 dissertations were defended, including a doctoral one. She published 250 works, 6 monographs and had 1 invention patent.
She is also a member of the Presidium of the Union of Kuzbass Women. She was awarded the medal “For the Special Contribution to the Development of Kuzbass” of III degree, the “Medal of Honor of Kuzbass”. She is a freeman of Kuzbass.Article Details
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References
; (4): 7-11. Russian (Ушакова Г.А. Биофизические механизмы гравидарного гомеостаза //Мать и Дитя в Кузбассе. 2014. № 4. С. 7-11)
Ushakova GA, Petrich LN. Gravidary homeosis with physiological pregnancy. Mother and Child in Kuzbass. 2012; (1): 63-69. Russian (Ушакова Г.А., Петрич Л.Н. Гравидарный гомеокинез при физиологической беременности //Мать и Дитя в Кузбассе. 2012. № 1. С. 63-69)
Gruzinova EN, Gerasimova LI, Denisova TG, Vasilyeva EN. Clinical evaluation of the reproductive function of women with body weight deficit. Practical medicine. 2012; (57): 211-213. Russian (Грузинова Е.Н., Герасимова Л.И., Денисова Т.Г., Васильева Э.Н. Клиническая оценка репродуктивной функции женщин с дефицитом массы тела //Практическая медицина. 2012. № 57. С. 211-213)
Gumenyuk EG, Kolosova TA, Nasonkova TI. The course of the first trimester of pregnancy in women with low body mass index and the possibility of preventing complications. Bulletin of the Russian University of Peoples' Friendship. 2011; (5): 158-163. Russian (Гуменюк Е.Г., Колосова Т.А., Насонкова Т.И. Течение I триместра беременности у женщин с низким индексом массы тела и возможности профилактики осложнений //Вестник Российского университета дружбы народов. 2011. № 5. С. 158-163)
Gundarov IA, Boyko NN. Deficiency of body weight as a risk factor for miscarriage (population study). Obstetrics and Gynecology. 2006; (6): 18-20. Russian (Гундаров И.А., Бойко Н.Н. Дефицит массы тела как фактор риска невынашивания беременности (популяционное исследование) //Акушерство и гинекология. 2006. № 6. С. 18-20)
Enikeev BV. Peculiarities of the course of pregnancy and its outcome in women with body weight deficit: Abstract dis. … cand. med. sciences. St. Petersburg, 2009. 21 p. Russian (Еникеев Б.В. Особенности течения беременности и ее исход у женщин с дефицитом массы тела: автореф. дис. … канд. мед. наук. СПб., 2009. 21 с.)
Abramchenko VV. Pregnancy and childbirth of high risk. M., 2004. 424 p. Russian (Абрамченко В.В. Беременность и роды высокого риска. М., 2004. 424 с.)
Sidorova TN, Bushueva EV, Gerasimova LI, Vasilyeva EN, Denisova TG. Monitoring of risk factors for the birth of children with intrauterine growth retardation syndrome. Public health and public health. 2010; (2): 73-74. Russian (Сидорова Т.Н., Бушуева Э.В., Герасимова Л.И., Васильева Э.Н., Денисова Т.Г. Мониторинг факторов риска рождения детей с синдромом задержки внутриутробного развития //Общественное здоровье и зравоохранение. 2010. № 2. С. 73-74)
Baevsky RM, Ivanov GG. Heart rate variability: theoretical aspects and possibilities of clinical application. Ultrasound and functional diagnostics. 2001; (3): 106-127. Russian (Баевский Р.М., Иванов Г.Г. Вариабельность сердечного ритма: теоретические аспекты и возможности клинического применения //Ультразвук и функциональная диагностика. 2001. № 3. С. 106-127)
Heart rate variability: Standards of measurement, physiological interpretation and clinical use. St. Petersburg, 2000. 63 p. Russian (Вариабельность сердечного ритма: Стандарты измерения, физиологической интерпретации и клинического использования. СПб., 2000. 63 с.)
Mikhailov VM. The variability of the rhythm of the heart. Experience of practical application of the method. Ivanovo, 2000. 182 p. Russian (Михайлов В.М. Вариабельность ритма сердца. Опыт практического применения метода. Иваново, 2000. 182 с.)
Rec YuV, Ushakova GA. Method for predicting pregnancy, patent number 2005117668 of the Federal Institute of Industrial Property, Moscow, 2007. Russian (Рец Ю.В., Ушакова Г.А. Способ прогнозирования беременности, патент № 2005117668 Федерального института промышленной собственности, г. Москва, 2007 г.)
Fleishman AN. Slow fluctuations in hemodynamics. Theory, practical application in clinical medicine and prevention. Novosibirsk, 1999. 224 p. Russian (Флейшман А.Н. Медленные колебания гемодинамики. Теория, практическое применение в клинической медицине и профилактике. Новосибирск, 1999. 224 с.)
Glukhovets BI, Glukhovets NG. Pathology afterbirth. St. Petersburg, 2002. 447 p. Russian (Глуховец Б.И., Глуховец Н.Г. Патология последа. СПб., 2002. 447 с.)
Milovanov AP. Pathology of the mother-placenta-fetus system: the management for doctors. M., 1999. 447 p. Russian (Милованов А.П. Патология системы мать-плацента-плод: руководство для врачей. М., 1999. 447 с.)