CLINICAL CASES OF LATE DIAGNOSIS OF MALIGNANT LYMPHADENOPATHY IN CHILDREN AND ADOLESCENTS
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Abstract
Lymph node enlargement syndrome in children and adolescents is one of the most frequent reasons for seeking medical care worldwide. We present clinical cases of difficult diagnosis of LAP.
Objective of the study – to analyze clinical cases of late diagnosis of malignant lymphadenopathy.
Materials and Methods. We analyzed 47 histories of patients aged 0 to 18 years who were admitted to the hospital with a provisional diagnosis of lymphadenopathy between January 2018 and June 2022.
Results. The most frequently observed lymph node enlargement in the cervical and submandibular regions was 1.1 to 2.5 cm. Enlarged supraclavicular and/or subclavian lymph nodes were associated with cancer in 100 % of cases. The median age of patients with malignant lymphadenopathies was 12 years. Boys predominated, 61.5 % versus 38.5 % of girls. The period from the detection of symptoms to hospitalization was long and was 1.5 months.
Conclusion. In children, lymphadenopathy is most often reactive. Detection of enlarged lymph nodes in children older than 10 years old requires inclusion of cancer in the circle of differential diagnosis.
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Author Biographies
Григорий Михайлович Сергиенко,
post-graduate student, department of pediatrics and neonatologyМарина Михайловна Котович,
Kotovich Marina MikhailovnaMD, PhD, professor.
She is a Professor at the Department of Pediatrics, Neonatology and Сlinical Pharmacology of the Novokuznetsk State Institute of Advanced Medical. She is a member of Russian Organization of Liver Diseases and Russian Gastroenterology Organization.
She graduated from the Pediatric Faculty of Kemerovo Medical institute in 1983. She defended her dissertation for the degree of Candidate of Medical Sciences on the theme “Autoimmune Hepatitis in Children (clinical picture, morphology, treatment)” in 1995 and her doctoral thesis on the theme “The Role of Etiotropic and Pathogenetic Therapy in Clinical and Morphological Evolution of Chronic Hepatitis in Children”.
She is an author of more than 120 scientific works and 2 scientific methodological manuals. She always upgrades her professional level, makes scientific reports within important Russian and International forums. In 2000 her report for “Hepatology Today” Congress was awarded a the 1st degree diploma.
She is a highly qualified pediatrician, multifunctional worker, whose priorities are hematology, immunology, perinatal pathology, congenital and hereditary diseases. She has developed and implemented into the practice methods of early diagnostics of mentioned disorders, more effective methods of treatment (including fatality and disability prevention). She regularly upgrades her professional and pedagogical skills, She also provides broad advice to practical health care.Марина Юрьевна Горошкова,
candidate of medical sciences, head of the department of pediatric oncology and hematologyЕлена Петровна Шабашкевич,
pediatric hematologist, department of pediatric oncology and hematologyНаталья Владимировна Селиванова,
pediatric oncologist, department of pediatric oncology and hematologyArticle Details
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The authors declare that they have no apparent or potential conflicts of interest related to the publication of this article.
This work is licensed under a Creative Commons Attribution 4.0 License.
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