TO THE DIFFERENTIAL DIAGNOSIS OF MULTISYSTEM INFLAMMATORY SYNDROME IN CHILDREN ASSOCIATED WITH A NEW CORONAVIRUS INFECTION
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Abstract
Pediatric inflammatory multisystem syndrome (MIS-C), or «pediatric multisystem inflammatory syndrome temporarily associated with SARS-COV-2 (PMIS-PT)» is a rare, severe complication or manifestation of new coronavirus infection. Clinical and laboratory symptoms of this disease (fever, rash, myocarditis, abdominal pain and other gastrointestinal symptoms; increased levels of CRP, procalcitonin, D-dimer, troponin and others) may be found in Kawasaki syndrome, severe bacterial infections, collagenosis, vasculitis. Despite the existing criteria, there may be doubts in establishing the diagnosis. This article presents clinical observations demonstrating certain difficulties in the differential diagnosis of MIS-C.
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Author Biographies
Марина Михайловна Котович,
Kotovich Marina MikhailovnaMD, PhD, professor.
She is a Professor at the Department of Pediatrics, Neonatology and Сlinical Pharmacology of the Novokuznetsk State Institute of Advanced Medical. She is a member of Russian Organization of Liver Diseases and Russian Gastroenterology Organization.
She graduated from the Pediatric Faculty of Kemerovo Medical institute in 1983. She defended her dissertation for the degree of Candidate of Medical Sciences on the theme “Autoimmune Hepatitis in Children (clinical picture, morphology, treatment)” in 1995 and her doctoral thesis on the theme “The Role of Etiotropic and Pathogenetic Therapy in Clinical and Morphological Evolution of Chronic Hepatitis in Children”.
She is an author of more than 120 scientific works and 2 scientific methodological manuals. She always upgrades her professional level, makes scientific reports within important Russian and International forums. In 2000 her report for “Hepatology Today” Congress was awarded a the 1st degree diploma.
She is a highly qualified pediatrician, multifunctional worker, whose priorities are hematology, immunology, perinatal pathology, congenital and hereditary diseases. She has developed and implemented into the practice methods of early diagnostics of mentioned disorders, more effective methods of treatment (including fatality and disability prevention). She regularly upgrades her professional and pedagogical skills, She also provides broad advice to practical health care.Яков Яковлевич Яковлев,
candidate of medical sciences, docent, acting head of the department of pediatrics and neonatologyГригорий Михайлович Сергиенко,
post-graduate student, department of pediatrics and neonatologyНаталья Владимировна Матвеева,
candidate of medical sciences, head of the pediatric departmentАлександр Иванович Требунских,
pediatric cardiologistЮлия Германовна Гельд,
head of the pathoanatomical departmentArticle Details
Information about financing and conflict of interests
The authors declare that they have no apparent or potential conflicts of interest related to the publication of this article.
This work is licensed under a Creative Commons Attribution 4.0 License.
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References
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