CLINICAL AND ANAMNESTIC CHARACTERISTICS AND FEATURES OF THE COURSE OF PREGNANCY IN WOMEN WITH PREMATURE RUPTURE OF MEMBRANES AT TERM
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Abstract
Prelabor rupture of membranes (PROM) at term remains a significant issue in modern obstetrics and is associated with an increased risk of maternal and neonatal complications. Studying clinical and anamnestic characteristics and pregnancy course in this group of women is essential for optimizing management strategies and preventing adverse outcomes.
Aim – to investigate the clinical and anamnestic profile of women with term prelabor rupture of membranes and to identify features of pregnancy course in a regional obstetric hospital.
Materials and Methods. A retrospective cross-sectional study included 100 women with term PROM (≥ 37 weeks of gestation) who delivered in 2024 at the maternity unit of the Kuzbass Regional Children’s Clinical Hospital named after Yu.A. Atamanov. Sociodemographic characteristics, somatic, gynecological and obstetric history, pregnancy complications, and laboratory findings were analyzed. Statistical analysis was performed using StatTech v.4.9.5 software.
Results. The median age of the patients was 26 [22-33] years. Most women were urban residents (71%), employed (64%), and had secondary vocational education (43%). Somatic comorbidities were common, with the highest prevalence of eye diseases (22%), urinary system disorders (20%), and cardiovascular diseases (16%). Overweight and obesity were observed in 20% of cases.
Reproductive history analysis revealed induced abortions in 20% of women, missed miscarriages and spontaneous abortions in 12%. Pregnancy complications occurred in 31% of patients, with gestational anemia (47%), gestational hypertension (11%), and urinary tract infections being the most frequent. Vaginal infections during pregnancy were diagnosed in 59% of women, predominantly bacterial vaginosis (43%).
Conclusion. Women with term prelabor rupture of membranes demonstrate a high prevalence of somatic and obstetric comorbidities as well as a significant burden of adverse reproductive history. These findings highlight the need for a comprehensive and individualized approach to pregnancy management in this population to reduce complications and improve maternal and perinatal outcomes.
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