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Марина Борисовна Игитова
Татьяна Ивановна Горбачева
Галина Викторовна Немцева
Елена Викторовна Мегрелидзе

Abstract

A study of concentrations of stable metabolites of nitric oxide in the blood serum of 82 patients with threatened abortion in the first trimester and 80 women with physiological early gestation was conducted. Stable metabolites of nitric oxide concentrations has been significantly reduced and amounted 9,06 ± 0,31 mcmol/l in women with threatened abortion (in the comparison group – 9,98 ± 0,29 mcmol/l, p = 0,023), that reflecting utero-placental homeostasis disorders in complicated early pregnancy. Stable metabolites of nitric oxide concentrations has an increased to the level of an uncomplicated pregnancy in the progestogen therapy.

Keywords

pregnancy, threatened abortion, nitric oxide

Author Biographies

Марина Борисовна Игитова,
doctor of medical sciences, professor, chair of obstetrics and gynecology N 2
Татьяна Ивановна Горбачева,
candidate of medical sciences, docent, department of obstetrics and gynecology
Галина Викторовна Немцева,
candidate of medical sciences, docent, department of obstetrics and gynecology
Елена Викторовна Мегрелидзе,
candidate of medical sciences, docent, department of obstetrics and gynecology

Article Details

Information about financing and conflict of interests

The study had no sponsorship.
The authors declare that they have no apparent or potential conflicts of interest related to the publication of this article.

How to Cite

Игитова, М. Б., Горбачева, Т. И., Немцева, Г. В., & Мегрелидзе, Е. В. (2017). CORRECTION OF EARLY UTERO-PLACENTAL HOMEOSTASIS DISORDERS IN WOMEN WITH THREATENED ABORTION. Mother and Baby in Kuzbass, 17(3), 42-44. https://www.mednauki.ru/index.php/MD/article/view/100

References

Вихляева, Е.М. Доклинические проявления системных нарушений, клинические исходы и отдаленные последствия преэклампсии /Е.М. Вихляева //Акушерство и гинекология. – 2009. – № 1. – С. 3-6

Эндотелиальная дисфункция в генезе перинатальной патологии /Г.Т. Сухих, Е.М. Вихляева, Л.В. Ванько и др. //Акушерство и гинекология. – 2008. – № 5. – С. 3-7

Авдеева, М.В. Особенности нейрогуморальной регуляции системы кровообращения при физиологической беременности /М.В. Авдеева, Л.В. Щеглова //Акушерство и гинекология. – 2007. – № 4. – С. 3-5

Сигнальные молекулы – маркеры зрелости плаценты /И.М. Кветной, Э.К. Айламазян, Е.А. Лапина, А.В. Колобов. – М.: МЕДпресс-информ, 2005. – 96 с.

Nitric oxide levels and endothelial nitric oxide synthase gene polymorphisms in Turkish women with idiopathic recurrent miscarriage /E. Oztürk, O. Balat, S. Pehlivan et al. //J. Turk. Ger. Gynecol. Assoc. – 2011. – N 4. – P. 234-238

Maternal and perinatal out-come in women with threatened miscarriage in the first trimester: a systematic review /L. Saraswat, S. Bhattacharya, A. Maheshwari //BJOG. – 2010. – V. 117. – P. 245-257

Ших, Е.В. Клинико-фармакологические аспекты применения дидрогестерона для сохранения беременности [Текст] /Е.В. Ших //Акушерство. Гинекология. Репродукция. – 2010. – Т. 4, № 2. – С. 6-9

Florkowski, C.M. Sensitivity, Specificity, Receiver-Operating Characteristic (ROC) Curves and Likelihood Ratios: Communicating the Performance of Diagnostic Tests /C.M. Florkowski //Clin. Biochem. Rev. – 2008. – V. 29, N 1. – P. 83-87

Nitric oxide levels in women with missed and threatened abortion: results of a pilot study /R. Paradisi, R. Fabbri, C. Battaglia et al. //Fertil. Steril. – 2007. – V. 88, N 3. – P. 744-748

Nitric oxide platelet production in spontaneous miscarriage in the first trimester /F. Raffaelli, L. Nanetti, A. Vignini et al. //Fertil. Steril. – 2010. – V. 93, N 6. – P. 1976-1982

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