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Татьяна Николаевна Елкина
Наталья Игоревна Пирожкова
Ольга Александровна Грибанова
Маргарита Геннадьевна Лиханова

Abstract

The aim of the research – assess the clinical and epidemiological features of the varicella and analyze the treatment tactics of children with varicella in the polyclinics of the Novosibirsk city.

Materials and methods. An analysis of 100 outpatient cards of children (age range from 8 months to 14 years) who had varicella and were on an outpatient treatment was carried out in 2013-2016.

Results. The majority of patients are school- and day care children with a burdened epidemiological history, the average age of 4.9 years, who had varicella of light severity. The greatest number of cases was observed from April to July. The disease proceeded on a favorable premorbid background and had a benign course. The duration of the disease averaged 11 days. The intoxication syndrome manifested mainly with a fever lasting 3.1 days. The number of patients with abundant and uneventful rashes was identical. The duration of the exanthema syndrome was 4.7 days. Symptomatic treatment consisted of use of antihistamines and staining of the elements with aniline dyes and antipyretic drugs. Anaferon for children and acyclovir were most commonly used among the etiotropic therapy medicamentations.

Conclusion. The Novosibirsk region is an area with high rates of varicella morbidity, higher than Russia’s average by 15-30 % over the past seven years. The structure of the affected by the disease is similar to the country average. The change in seasonality is registered, with the rise in the incidence rate in the spring-summer period. Diagnosis was carried out taking into account the basic diagnostic signs: an indication of contact with the varicella patient, the presence of symptoms of intoxication, fever and a typical exanthema. Most patients received only symptomatic treatment. Anaferon for children was most commonly used among the etiotropic therapy medicamentations. The unique mode of action of RAII (Release-Active Interferon Inducers) explains the wide possibilities for their application, especially for children with relatively mild chiken pox. The approval of the primary health care standard for children with moderate varicella would help to regulate the approach for the antiviral drugs selection and avoid polyprogram treatment.

Keywords

varicella, children, etiotropic therapy

Author Biographies

Татьяна Николаевна Елкина,
doctor of medical sciences, professor, head of the department of outpatient pediatrics
Наталья Игоревна Пирожкова,
candidate of medical sciences, docent, department of outpatient pediatrics
Ольга Александровна Грибанова,
candidate of medical sciences, docent, department of outpatient pediatrics
Маргарита Геннадьевна Лиханова,
candidate of medical sciences, docent, department of outpatient pediatrics

Article Details

Information about financing and conflict of interests

The study had no sponsorship.
The authors declare that they have no apparent or potential conflicts of interest related to the publication of this article.

How to Cite

Елкина, Т. Н., Пирожкова, Н. И., Грибанова, О. А., & Лиханова, М. Г. (2019). CLINICAL PRACTICE OF MANAGEMENT OF VARICELLA AT CHILDREN AT THE PRE-HOSPITAL STAGE IN NOVOSIBIRSK CITY. Mother and Baby in Kuzbass, 20(1), 20-25. https://www.mednauki.ru/index.php/MD/article/view/245

References

Voronin EM. Modern epidemiological features of varicella and approaches to its prevention. Author's abstract … cand. of med. sci. M., 2012. 24 p. Russian (Воронин Е.М. Современные эпидемиологические особенности ветряной оспы и подходы к её профилактике. Автореф. дис. ... канд. мед. наук. М., 2012. 24 с.)

Ermolenko M. V. Serological monitoring in the system of epidemiological surveillance of varicella. Author's abstract … cand. of med. sci. M., 2014. 103 p. Russian (Ермоленко М.В. Серологический мониторинг в системе эпидемиологического надзора за ветряной оспой. Автореф. дис. ... канд. мед. наук. М., 2014. 103 с.)

Meeting of the International expert Council on prevention and control of varicella in Europe. Pediatric Pharmacology. 2010; 7(1): 91-95. Russian (Заседание Международного экспертного совета по вопросам профилактики и борьбы с ветряной оспой в Европе //Педиатрическая фармакология. 2010. Т. 7, № 1. С. 91-95)

Lobzin YuV, Skripchenko EYu, Karev VE, Palchik AB. Congenital chickenpox: urgency and clinical case. Russian Bulletin of Perinatology and Pediatrics. 2012; 57(2): 64-70. Russian (Лобзин Ю.В., Скрипченко Е.Ю., Карев В.Е., Пальчик А.Б. Врождённая ветряная оспа: актуальность, проблемы и клинический случай //Российский вестник перинатологии и педиатрии. 2012. Т. 57, № 2. С. 64-70)

Order of the Ministry of Health of the Russian Federation of March 21, 2014 No. 125n «On approval of the national preventive vaccination calendar and preventive vaccination calendar for epidemic indications». Russian (Приказ Минздрава РФ от 21.03.2014 г. № 125н «Об утверждении национального календаря профилактических прививок и календаря профилактических прививок по эпидемическим показаниям»)

Clinical guidelines (treatment protocol) provision of medical care for children sick with chickenpox. M., 2015. 61 p. Russian (Клинические рекомендации (Протокол лечения) оказания медицинской помощи детям больным ветряной оспой. М., 2015. 61 с.)

Order of the Ministry of Health of Russia dated 09.11.2012 N 743n «On approval of the standard of specialized medical care for children with chickenpox of moderate severity». Russian (Приказ Минздрава России от 09.11.2012 N 743н «Об утверждении стандарта специализированной медицинской помощи детям при ветряной оспе средней степени тяжести»)

Chernova TM, Timchenko VN. Modern Aspects of Antiviral Therapy of Varicella in Children. Children's Infections. 2011; 10 (3): 58-61. Russian (Чернова Т.М., Тимченко В.Н. Современные аспекты противовирусной терапии ветряной оспы у детей //Детские инфекции. 2011. Т. 10, № 3. С. 58-61)

Zhavbert ES, Dugina YuL, Epstein OI. Immunotropic Properties of Anaferon and Anaferon Pediatric. Antibiotics and chemotherapy. 2013; 58(5-6): 17-23. Russian (Жавберт Е.С., Дугина Ю.Л., Эпштейн О.И. Иммунотропные свойства анаферона и анаферона детского //Антибиотики и химиотерапия. 2013. Т. 58, № 5-6. С. 17-23)

Tarasov SA, Kachanova MV, Gorbunov EA, Zabolotneva JA, Kheifets IA, Belopolskaya MV et al. Anaferon – effective medicine for treatment and prophylaxis a wide spectrum of infections. Herald of the International Academy of Sciences. Russian Section. 2010; 1: 23-27. Russian (Тарасов С.А., Качанова М.В., Горбунов Е.А., Заболотнева Ю.А., Хейфец И.А., Белопольская М.В. и др. Анаферон – эффективное средство для лечения и профилактики широкого спектра инфекционных заболеваний //Вестник Международной академии наук (Русская секция). 2010. № 1. С. 23-27)

Shamsheva OV. Experiences with Anaferon in pediatric patients. Effective pharmacotherapy. 2013; 27: 38-44. Russian (Шамшева О.В. Опыт применения Анаферона в педиатрической практике //Эффективная фармакотерапия. 2013. № 27. С. 38-44)

Lobzin YuV, De Rosa F, Esaulenko EV. National and foreign research of Anaferon Kid: efficacy, safety and experience of application (review). Journal of Infectology. 2015; 7(4): 23-31. Russian (Лобзин Ю.В., Де Роза Ф., Эсауленко Е.В. Отечественные и зарубежные исследования анаферона детского: эффективность, безопасность и опыт применения (обзор литературы) //Журнал инфектологии. 2015. Т. 7, № 4. С. 23-31)

Kudin MV, Feodorov YN, Skripkin AV, Tarasov SA, Dugina YL, Sergeyeva SA, Epshtein OI. Clinical efficiency of using infantine Anaferon in treating children/infants suffering from Chickenpox. Children's Infections. 2007; 6(4): 61-68. Russian (Кудин М.В., Федоров Ю.Н., Скрипкин А.В., Тарасов С.А., Дугина Ю.Л., Сергеева С.А., Эпштейн О.И. Клиническая эффективность применения Анаферона детского в лечении ветряной оспы у детей //Детские инфекции. 2007. Т. 6, № 4. С. 61-68)

Kladova OV, Epstein OI, Ivakhina LI, Sergeeva SA, Kachanova MV, Yablonskaya KP. Antiviral Therapy of Varicella in Children. Children's Infections. 2010; 9(2): 46-49. Russian (Кладова О.В., Эпштейн О.И., Ивахина Л.И., Сергеева С.А., Качанова М.В., Яблонская К.П. Противовирусная терапия ветряной оспы у детей //Детские инфекции. 2010. Т. 9, № 2. С. 46-49)

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